Semax is a synthetic analog of the adrenocorticotropic hormone (ACTH) fragment 4-10. It was originally developed to investigate cognitive enhancement and neuroprotection in settings of brain ischemia and hypoxia. Unlike the parent hormone, Semax is devoid of hormonal activity but possesses significant neurotrophic properties. In research settings, it is primarily studied for its ability to increase the levels of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). This heptapeptide serves as a vital reagent for exploring synaptic plasticity, memory formation, and the cellular mechanisms of neurorecovery following injury. Its stable, lyophilized form ensures consistency in neurochemical and behavioral assays.