KPV is a synthetic tripeptide fragment (Lys-Pro-Val) derived from the alpha-melanocyte–stimulating hormone ($\alpha$-MSH) sequence. It has been widely studied for its anti-inflammatory, antimicrobial, and tissue-protective properties, particularly in research exploring immune regulation and barrier-function restoration. In preclinical research, KPV has demonstrated the ability to modulate NF-κB activity, reduce pro-inflammatory cytokine release, and enhance epithelial repair responses. These characteristics make it a valuable tool for immunology, dermatology, and gastrointestinal-barrier research models.